Endocrine Abstracts

Both metabolism and cardiac function fluctuate over the course of the day according to energy supply and demand. The triiodothyronine (T3) regulates several genes related to metabolism and function in cardiomyocytes. Our previous data have suggested that there is a potential interrelationship between the regulation of cardiac function by T3 and the intrinsic circadian clock in the heart. Considering that: i) the hypothyroidism is associated to a reduction...